Eczema, a persistent skin condition marked by redness, itching, and inflammation, casts its shadow over millions globally. Finding effective treatments for eczema, despite its widespread impact, has proven to be a persistent and perplexing challenge for those working to address it.

However, CBD (cannabidiol), a non-psychoactive cannabis derivative, has recently gained widespread attention for its potential therapeutic effects. In this article, we delve into the scientific mechanisms that underlie CBD’s efficacy in treating eczema.

Symptoms of Eczema

Before delving into the potential benefits of CBD for eczema, it’s crucial to understand the condition itself. Eczema, also known as atopic dermatitis, is a chronic skin disorder characterized by several uncomfortable and sometimes painful symptoms. These symptoms include, but may not be limited to:

  • Itching
  • Redness and Inflammation
  • Dry and Flaky Skin
  • Blisters and Oozing
  • Skin Thickening
  • Psychological Impact

Common Causes of Eczema

Uncovering the precise causes of eczema is an ongoing scientific endeavor that is intertwined with the possibilities of genetic factors, environmental influences, and immune system issues. While the precise trigger remains unknown, examining these elements will provide profound insights into the possible causes of eczema.

Genetic Predisposition

Genetic predisposition is at the forefront of eczema’s complex story. The familial landscape of an individual, particularly those characterized by eczema, allergic rhinitis, or asthma, sets the stage for potential eczema development.

Immune System Dysfunction

The immune system protects the body’s intricate defense mechanism against external threats. However, a discordant response emerges in those affected by eczema. The immune system, which is hyper-vigilant in those with eczema, may react exaggeratedly to triggers, causing inflammation and skin distress. This heightened immune response is the driving force behind eczema’s hallmark symptoms of redness, itching, and inflammation.

Skin Barrier Dysfunction

A compromised skin barrier, which is common in eczema patients, makes the skin more vulnerable to external stimuli. This vulnerability is caused by a complex interplay of genetic factors, environmental pressures, and disruptions in skin protein production, allowing irritants to breach the skin’s defenses and incite inflammatory turmoil.

Environmental Triggers

Environmental factors play a significant role in triggering or exacerbating eczema symptoms. Common environmental triggers include:

  • Exposure to allergens like pollen, pet danger, dust mites, and certain foods.
  • Irritants such as harsh soaps, detergents, fragrances, and chemicals in skincare products.
  • Extreme temperatures, humidity levels, or sudden changes in weather.
  • Bacterial, viral, or fungal infections.
  • Increase in stress and/or anxiety.
  • Hormonal changes, particularly in women, such as those occurring during puberty, pregnancy, and menstruation.

Traditional Treatments for Eczema

Managing eczema often involves a combination of lifestyle modifications and medical treatments. Common approaches include:

  • Emollients and Moisturizers
  • Topical Steroids
  • Topical Calcineurin Inhibitors
  • Oral Antihistamines
  • Phototherapy
  • Immunosuppressants

While these traditional treatments can provide relief for many individuals with eczema, they may not be effective for everyone. Moreover, some of them come with potential side effects and limitations, leading people to seek alternative therapies like CBD.

CBD and The Endocannabinoid System

Cannabidiol (CBD), a natural compound within the cannabis plant, stands as one among the 100-plus naturally occurring compounds. Unlike its counterpart, tetrahydrocannabinol (THC), CBD steers clear of inducing psychoactive effects. Instead, it engages with the endocannabinoid system (ECS), an intricate regulatory network present in all mammals.

The ECS assumes a pivotal role in preserving bodily equilibrium, overseeing a spectrum of physiological functions such as pain perception, immune response, mood, and skin health. Its structure comprises three essential components:

  1. Endocannabinoids: These are intrinsic compounds the body produces naturally, binding to cannabinoid receptors.
  2. Cannabinoid Receptors: Distributed throughout the body, these receptors are classified into two main types — CB1 receptors, primarily situated in the brain and central nervous system, and CB2 receptors, predominantly located in immune cells and peripheral tissues.
  3. Enzymes: Responsible for breaking down endocannabinoids after they’ve fulfilled their function.

CBD orchestrates its interaction with the ECS by influencing cannabinoid receptor activity, with a particular focus on CB1 and CB2 receptors. However, this interaction, while intricate, differs from the more direct influence exerted by THC.

How CBD Can Help Ease Eczema Symptoms

CBD’s Anti-Inflammatory Properties for Eczema

CBD’s effectiveness in treating eczema is attributed to its potent anti-inflammatory properties. Numerous studies have shown that CBD can significantly reduce skin inflammation, potentially alleviating the redness and swelling associated with eczema. CBD, by modulating inflammatory responses, may provide relief to people suffering from the discomfort of eczema flare-ups.

CBD’s Pain Relief for Eczema-Related Discomfort

The itching and discomfort associated with eczema can be particularly distressing. CBD’s analgesic or pain-relieving properties present a promising avenue for alleviating the pain caused by eczema-related symptoms. By interacting with the body’s endocannabinoid system, CBD may help mitigate the sensory aspects of pain, providing individuals with eczema with a natural and potentially effective means of managing their discomfort.

CBD’s Anti-Itch Effects in Eczema

Itchiness is a hallmark symptom of eczema that significantly impacts the quality of life for those affected. CBD’s interaction with receptors in the skin suggests anti-itch effects, potentially modulating the sensation of itch. This mechanism offers hope for individuals with eczema, providing a targeted approach to reduce the persistent and often overwhelming urge to scratch, which can worsen the condition.

CBD’s Contribution to Skin Barrier Enhancement in Eczema

Maintaining a healthy skin barrier is crucial for individuals with eczema, as a compromised barrier can lead to increased sensitivity and susceptibility to irritants. CBD has been studied for its potential to enhance the skin barrier function. Such enhancement may offer protective benefits, helping eczema-prone skin better withstand environmental factors and reducing the likelihood of flare-ups.

CBD’s Immunomodulatory Effects in Eczema

Eczema is often associated with an overactive immune response that leads to chronic inflammation. CBD’s immunomodulatory effects make it a compelling candidate for regulating this hyperactive immune response seen in eczema. By influencing the immune system, CBD may contribute to a reduction in inflammation, ultimately alleviating the severity of eczema symptoms.

CBD’s Moisturizing Properties for Eczema-Prone Skin

Dry and flaky skin is a common manifestation of eczema, necessitating effective moisturization. CBD-infused creams and lotions often contain moisturizing ingredients that complement CBD’s potential benefits. These formulations may provide individuals with eczema the dual advantage of CBD’s therapeutic properties along with essential hydration, promoting healthier and more resilient skin.

CBD’s Anti-Bacterial Effects and Eczema Management

Secondary skin infections pose a significant concern for individuals with eczema, especially when the skin’s integrity is compromised. CBD’s potential anti-bacterial properties present an intriguing aspect of eczema management. CBD may contribute to the overall well-being of eczema sufferers by lowering the risk of bacterial infections, addressing a common challenge associated with the condition.

Scientific Evidence and Studies

While the potential benefits of CBD for eczema are promising, it’s essential to acknowledge that research in this area is still relatively limited, and more comprehensive clinical trials are needed. However, some preliminary studies and anecdotal evidence suggest that CBD may be a valuable addition to eczema management.

  1. A 2019 study published in the journal “Clinical Therapeutics” examined the use of a CBD-infused ointment in 20 participants with mild to moderate atopic dermatitis (eczema). After just three weeks of treatment, participants experienced a significant reduction in skin itching and improved sleep quality.
  2. A 2020 study in the “Journal of Dermatological Science” explored the potential of CBD in managing acne, another inflammatory skin condition. While eczema and acne are distinct conditions, both involve inflammation and immune system dysregulation. The study found that CBD exhibited anti-inflammatory properties and regulated sebum production, which could have implications for eczema management.
  3. Anecdotal Reports: Many individuals with eczema have reported personal success with CBD products, sharing stories of symptom relief, improved skin texture, and reduced itching.

It’s important to note that individual responses to CBD can vary, and what works for one person may not work as effectively for another. Additionally, the quality and formulation of CBD products can significantly impact their efficacy.

Steps for Effective CBD Use in Eczema Management

  1. Consult Your Healthcare Provider

incorporating CBD into your eczema management plan, engage in a thorough discussion with your dermatologist or healthcare provider. Their insights can guide your decisions, ensuring a well-informed approach aligned with your specific situation.

  • Choose High-Quality Products

Not all CBD products offer the same quality. Seek out reputable brands that conduct third-party lab testing. This ensures the purity and potency of the CBD product, providing you with a reliable and effective option.

  • Consider the Formulation

CBD for eczema is available in various forms such as creams, lotions, balms, oils, and capsules. The choice of formulation should align with your personal preferences and the location/severity of your eczema. Tailoring the application method enhances the effectiveness of CBD.

  • Start with a Low Dose

If you’re new to CBD, initiate your usage with a low dose. Gradually increase it as needed, allowing your body to acclimate and minimizing the risk of adverse effects. This cautious approach facilitates a better understanding of your body’s response to CBD.

  • Patch Test

Prior to applying a CBD topical to a larger skin area, conduct a patch test on a small, inconspicuous area. This precautionary measure helps identify any potential allergic reactions or skin sensitivities, ensuring a safe experience.

  • Monitor Your Skin

Keep a vigilant eye on how your skin responds to CBD. Record any noticeable changes in symptoms, such as reduced itching or inflammation. Monitoring your skin’s reaction provides valuable insights into the effectiveness of CBD in addressing your eczema.

  • Be Patient

Recognize that CBD’s effects may not manifest immediately. Consistent use over several weeks is often necessary to observe noticeable improvements. Patience is key in allowing CBD the time it needs to work effectively.

  • Maintain Your Current Treatment Plan

CBD should complement, not replace, your existing eczema treatment plan, especially if prescribed by a healthcare professional. Integrating CBD as a complementary therapy ensures a holistic approach to eczema management.


CBD is at the forefront of potential eczema treatment. Its anti-inflammatory, analgesic, and skin-nourishing properties provide a fresh take on skincare and provide benefits to those suffering from skin conditions such as Eczema.

As research advances, CBD promises to be a complex ally for those seeking relief from eczema symptoms. With that said, it’s no doubt that we are optimistic about the possibilities CBD can have for our health. So, stay informed, and allow the changing CBD landscape to reshape your path to healthier skin.


A therapeutic effect of cbd-enriched ointment in inflammatory skin diseases and cutaneous scars – PubMed (

Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders – PMC (

5 Best CBD Creams for Eczema | Healthline